Journal article
Increasing airway obstruction from 8 to 18 years in extremely preterm/low-birthweight survivors born in the surfactant era
LW Doyle, AM Adams, C Robertson, S Ranganathan, NM Davis, KJ Lee, JL Cheong, P Anderson, A Burnett, C Callanan, E Carse, MP Charlton, J Duff, E Hutchinson, M Hayes, E Kelly, M McDonald, G Opie, G Roberts, A Watkins Show all
Thorax | BMJ PUBLISHING GROUP | Published : 2017
Abstract
Background: The evolution of airway obstruction into late adolescence of extremely preterm (gestational age <28 weeks) or extremely low-birthweight (birth weight <1000 g) survivors in the era after surfactant was introduced is unclear. Objective: To compare changes in spirometry from 8 to 18 years of age of a geographical cohort of preterm survivors with normal birth weight controls, and to determine higher risk groups within the preterm cohort. Methods: Of 297 extremely preterm/low-birthweight survivors born in 1991-1992 in the state of Victoria, Australia, 81% and 70% had spirometry at 8 and 18 years of age, respectively. Corresponding rates among 260 normal birth weight controls were 80% ..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
National Health and Medical Research Council of Australia: Project Grant #491246; Program Grant #606789; Centre of Clinical Research Excellence Grant #546519; Centre of Research Excellence Grant #1060733; Early Career Fellowship Grant #1053787. Victorian Government's Operational Infrastructure Support Program.